KimaCell®HPMC K200M is used as tablet drug skeleton or capsule shell for drug-loaded sustained-release system. HPMC is a hydrophilic high-molecular polymer and can be used as a erodible tablet skeleton material to play the dual role of drug storage and controlled rapid drug release. In addition, controlled-release tablet drugs also have the advantages of being easy to take and easy to carry.
HPMC K200M ( 9004 65 3 ) Hydroxypropyl Methyl Cellulose (HPMC) | |
Physical Analysis | |
Appearance | White to slightly off-white fibrous or granular powder. |
Identification A to E | Conform |
Solution appearance | Conform |
Methoxy | 19.0-24.0% |
Hydroxypropoxy | 4.0-12.0% |
Loss on drying | 5.0% Max |
Residue on ignition | 1.5% Max |
pH | 5.0-8.0 |
Apparent viscosity | 160000.0-240000.0cps |
Particle size | Min. 98% pass through 100 mesh |
Heavy Metals | |
Heavy Metal | ≤10ppm |
Arsenic | ≤3ppm |
Lead | ≤3ppm |
Mercury | ≤1ppm |
Cadmium | ≤1ppm |
Micro bacteria | |
Total plate count | ≤1000cfu/g |
Yeast and Mould | ≤100cfu/g |
Coli form | Absent/g |
Salmonella | Absent/g |
KimaCell® HPMC K200M is one of the natural cellulose derivatives, HPMC has been widely used in the pharmaceutical industry due to its abundant sources, low price, non-toxicity and good biocompatibility.
With the advancement of science and technology, people's understanding of diseases has become more and more in-depth, and the treatment methods have become diverse. As a new treatment method, stem cell culture for the treatment of diseases has aroused great interest of medical workers. As a highly hydrophilic natural polymer material, HPMC can simulate the extracellular matrix, is non-toxic and has good biocompatibility, and can be used as a matrix for stem cell culture, and has a wide range of applications in the clinical treatment of diseases.
In recent years, the application of HPMC in tissue engineering has also been extensively studied. As a kind of biological material, HPMC is prepared into gel or functional scaffold by researchers due to its excellent characteristics, and it plays a huge role in the clinical treatment of some diseases caused by tissue loss or damage.