KimaCell®HPMC K15M is used as film coating and binder in pharmaceutical tablets, it can significantly improve the solubility of drugs and enhance the water resistance of tablets. It can also be used as suspension, ophthalmic preparation, sustained and controlled release agent matrix and floating tablet, etc. When HPMC K15M is combined with other synthetic polymers and colloidal drugs to prevent water and ethanol from separating from the transparent hydrocolloid and improve water retention, it is also used as a thickener, emulsifier and rheological properties. And other daily chemical industries, etc.
HPMC K15M ( 9004 65 3 ) Hydroxypropyl Methyl Cellulose (HPMC) | |
Physical Analysis | |
Appearance | White to slightly off-white fibrous or granular powder. |
Identification A to E | Conform |
Solution appearance | Conform |
Methoxy | 19.0-24.0% |
Hydroxypropoxy | 4.0-12.0% |
Loss on drying | 5.0% Max |
Residue on ignition | 1.5% Max |
pH | 5.0-8.0 |
Apparent viscosity | 12000.0-18000.0cps |
Particle size | Min. 98% pass through 100 mesh |
Heavy Metals | |
Heavy Metal | ≤10ppm |
Arsenic | ≤3ppm |
Lead | ≤3ppm |
Mercury | ≤1ppm |
Cadmium | ≤1ppm |
Micro bacteria | |
Total plate count | ≤1000cfu/g |
Yeast and Mould | ≤100cfu/g |
Coli form | Absent/g |
Salmonella | Absent/g |
HPMC K15M is a high-viscosity, water-soluble cellulose derivative known for its excellent thickening, gelling, and emulsifying properties. Its ability to form stable gel-like structures in aqueous solutions makes it highly effective in applications requiring viscosity control and consistent performance. Non-ionic and pH-stable, Methocel K15M offers versatility across a wide range of industries, including pharmaceuticals, food, cosmetics, and construction. Thanks to its high molecular weight, it excels in binding, suspending, and improving the texture of formulations, making it a key ingredient for enhancing product quality and functionality.
The viscosity of HPMC K15M (Hydroxypropyl Methylcellulose K15M) typically ranges from 12000.0-18000.0cps when dissolved at a 2% concentration in water at 20°C. This high viscosity makes it ideal for applications that require thickening, gelling, or suspending properties. The viscosity of HPMC K15M can be further customized by adjusting the concentration or modifying the formulation, providing flexibility for a variety of uses.
Superior Solubility
Kima Chemical's Methocel K15M dissolves rapidly in cold water, forming clear, stable solutions without requiring heat. This remarkable solubility makes it highly adaptable for a wide range of formulations, both in industrial and consumer product applications.
Consistent Quality and Purity:
Kima Chemical adheres to rigorous quality control processes to ensure that HPMC K15M meets the highest standards of purity and consistency. This commitment to quality is essential for industries such as pharmaceuticals, food, and cosmetics, where product reliability is critical.
Non-Ionic and pH Stability:
As a non-ionic polymer, Methocel K15M does not interact with other ingredients in formulations, ensuring that the effectiveness of other components is maintained. It is also stable across a wide pH range, making it versatile for various applications without compromising performance.
Thermal Gelation Properties:
A distinctive feature of wholesale HPMC K15M is its ability to gel at elevated temperatures. This thermal gelation property is especially beneficial for specific applications like controlled drug release systems or gel-based cosmetics, ensuring effective performance across varying temperature conditions.
KimaCell® HPMC K15M is widely used in injectable hydrogel. Injectable hydrogel is a type of hydrogel that can exist in a liquid state and be transported to the injection site, respond to certain stimuli such as temperature, ionic strength, etc., and can quickly complete the liquid-solid phase transition. Compared with traditional hydrogels, injectable hydrogels can maintain a liquid state in vitro after being loaded with drugs, and rapidly undergo a phase transition after entering the body, so that the drugs can be released continuously, improve the utilization rate of the drugs, and reduce the occurrence of side effects, achieving more good therapeutic effect. In situ gel is also a part of injectable gel. The unique solution-gel transition properties of in situ gel make it have the advantages of good tissue compatibility, long residence time, high local drug concentration and high bioavailability. HPMC is used as the matrix of some injectable in situ gels, which can be used for the treatment of some diseases that require high drug concentration and drug duration. Wholesale HPMC K15M is widely used in skin, eyes, mouth, nasal cavity, vagina, rectum, etc. way of administration.