KIMA CHEMICAL CO.,LTD.
KIMA CHEMICAL CO.,LTD.
HPMC E15

HPMC E15

KimaCell®HPMC E15 Hydroxypropylmethylcellulose is a water-soluble cellulose polymer that helps optimize the solubility enhancement of poorly soluble drugs by maintaining a stable solid dispersion and inhibiting API crystallization.

More sophisticated drug discovery techniques have resulted in pipeline compounds requiring enhanced solubility to achieve therapeutic efficacy. Solid dispersion is one of the key technologies for formulating oral solid dosage forms containing APIs with bioavailability challenges. HPMC E15 is specifically designed for the production of solid dispersions in the pharmaceutical industry by spray drying or hot melt extrusion.


Where to buy Cas 9004-65-3
HPMC E15

HPMC E15 Properties



HPMC E15

Hydroxypropyl Methyl Cellulose (HPMC)

Physical Analysis

Appearance

White to slightly off-white fibrous or granular powder.

Identification A to E

Conform

Solution appearance

Conform

Methoxy

28.0-30.0%

Hydroxypropoxy

7.0-12.0%

Loss on drying

5.0% Max

Residue on ignition

1.5% Max

pH

5.0-8.0

Apparent viscosity

12-18cps

Particle size

Min. 98% pass through 100 mesh

Heavy Metals

Heavy Metal

≤10ppm

Arsenic

≤3ppm

Lead

≤3ppm

Mercury

≤1ppm

Cadmium

≤1ppm

Micro bacteria

Total plate count

≤1000cfu/g

Yeast and Mould

≤100cfu/g

Coli form

Absent/g

Salmonella

Absent/g


What HPMC 15 CPS Means?

HPMC 15 CPS means Hydroxypropyl Methylcellulose with a viscosity of 15 centipoises (cps). It is a type of cellulose-based polymer commonly used in various industries, including pharmaceuticals, cosmetics, and construction. The "15 cps" specification indicates the viscosity of the HPMC solution, with higher numbers indicating thicker solutions. This viscosity is important for controlling the flow and thickness of products in which HPMC E15 is used, such as in pharmaceutical tablets.

HPMC E15 Viscosity

HPMC E15 refers to Hydroxypropyl Methyl Cellulose (9004 65 3)with a nominal viscosity of 12.0-18.0 centipoises (cPs). The viscosity of HPMC E15 can vary slightly depending on the concentration and temperature of the solution it is dissolved in. However, the nominal viscosity value of 12-18 mPa.s provides a general indication of its viscosity range.


Viscosity is a measure of a fluid's resistance to flow. In the case of HPMC E15, the higher viscosity indicates that it forms a more viscous solution compared to lower viscosity grades of HPMC. HPMC Methocel E 15 viscosity makes it suitable for applications that require thicker and more stable formulations.


It's important to note that the viscosity of HPMC Methocel E 15 can be further adjusted by varying the concentration of the HPMC powder in the solution. Higher concentrations of HPMC will generally result in higher viscosity solutions.


When using HPMC E15 in formulations, it is advisable to consult the manufacturer's technical data sheet or product specifications for precise information on viscosity and recommended usage levels. The technical data provided by the manufacturer of HPMC E 15 will offer detailed information on the viscosity range, methods of measurement, and guidelines for formulating with HPMC E15.


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HPMC E15 Uses


KimaCell® HPMC E15 is widely used in pharmaceutical excipients.

  • Tablet adhesive

    HPMC E15 can be used as a binder for wet granulation of tablets at 3-5% of the finished tablet weight. HPMC E15 produces stronger granules compared to granules made with HPMC E15, which means that disintegration and dissolution times may be affected as harder tablets are produced.

  • Thickener and suspending agent

    HPMC E15 can be used as a viscosity modifier in many cream, ointment, suspension formulations, including ophthalmic formulations.

    KimaCell E15 grade is used in systems where high transparency is required and ease of filtration is an important parameter.


Benefits of Choosing Kima Chemical's HPMC E15 Powder

  • High-Quality Manufacturing Standards

Kima Chemical has passed the lS09000 international quality system. Our automatic cellulose ether production line is equipped with state-of-the-art technology, ensuring precise control over critical factors like viscosity, solubility, and particle size, so our customers receive a reliable and high-performance product every time.

  • Pollution-Free, Closed Packaging System

At Kima Chemical, we are committed to maintaining the highest standards of hygiene and purity in Methocel E 15. Our fully automatic closed packaging system eliminates the risk of contamination during the production and packaging stages. This ensures that our HPMC E15 is delivered in pristine condition, preserving its quality, performance, and safety for all customer applications.

  • Large-Scale Production Capacity

Our advanced manufacturing facilities enable us to produce over 12 tons per batch, meeting the needs of large-scale industrial operations. With such a high production capacity, Kima Chemical can consistently supply HPMC E 15 Powder in bulk, ensuring that our customers never face supply shortages or delays.

  • 24/7 Customer Support

Kima Chemical has 20 years of experience in the cellulose ether industry. Our 365*24 after-sales service ensures that you have access to expert assistance whenever you need it.


Get In Touch With Kima Chemical
lf you have any questions about our cellulose ether products, please contact us.
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