HPC-M

Specification of HPC-M

Application of HPC-M

KimaCell^® HPC-M Hydroxypropyl cellulose mainly has two functions, the low-viscosity specification is used as a binder, and the high-viscosity specification is used as a hydrophilic gel sustained-release matrix tablet. As a binder, it has a solubilizing effect on the drug, which may be the effect of hydroxypropyl cellulose on inhibiting drug precipitation. Theoretically, the dissolution and precipitation of the drug are reverse reactions, and when the saturation concentration is reached, the equilibrium is reached, and the dissolution rate is equal to the precipitation rate. Hydroxypropyl cellulose has functional groups such as hydroxypropyl groups, which may interact with some drug groups and inhibit drug precipitation, thereby promoting the dissolution process to a certain extent, showing certain The solubilization effect is essentially the intermolecular interaction between the drug and the polymer.