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KIMA CHEMICAL CO.,LTD.
KIMA CHEMICAL CO.,LTD.

As an excipient, HPMC is an inactive ingredient that is used to improve the quality, safety, and effectiveness of drug products. Here are some of the main applications of HPMC in the pharmaceutical industry:

  • Controlled release: HPMC can be used to create controlled-release drug formulations that release the active ingredient at a controlled rate over an extended period of time. This can help to improve the efficacy of the drug and reduce the frequency of dosing.

  • Tablet coating: HPMC is a common binder used in tablet formulations. It helps to hold the tablet ingredients together, improving the tablet's structural integrity, and ensuring consistent dosage and disintegration.

  • Film coating: HPMC can be used as a film coating for tablets, vegetable capsules, and granules. It helps to protect the drug from environmental factors and improve its appearance and swallowability.

  • Disintegrant: HPMC can be used as a disintegrant in tablet formulations to help the tablet dissolve quickly and uniformly in the gastrointestinal tract. This can improve the bioavailability of the drug and enhance its therapeutic effect.

  • Suspending agent: HPMC can be used as a suspending agent to keep insoluble drug particles in suspension in liquid formulations, such as suspensions and emulsions.

Types of HPMC for Pharmaceutical

Types of HPMC for Pharmaceutical

How To Use HPMC for Pharmaceutical?

How To Use HPMC for Pharmaceutical?

HPMC (Hydroxypropyl methylcellulose) can be used to pharmaceutical excipient formulations using different methods depending on the application. Here are some general guidelines for adding HPMC in pharmaceuticals:

01.

Binder: HPMC can be added as a binder to the dry blend of tablet ingredients. The HPMC is typically added to the dry powder blend and mixed thoroughly. Water or another suitable solvent is then added to the blend to form a granulation that is dried and milled to the desired particle size. The resulting granules are then compressed into tablets using a tablet press.

02.

Disintegrant: HPMC can be added as a disintegrant to the dry blend of tablet ingredients. The HPMC is typically added to the dry powder blend and mixed thoroughly. Water or another suitable solvent is then added to the blend to form a granulation that is dried and milled to the desired particle size. The resulting granules are then compressed into tablets using a tablet press.


03.

Film coating: HPMC can be added to a coating solution for film-coating tablets. To prepare an HPMC film-coating solution, HPMC is usually dispersed in water or an organic solvent, along with plasticizers and other excipients. The resulting solution is then sprayed onto the surface of the tablet using a spray coating apparatus.

04.

Controlled release: HPMC can be added to a drug formulation to create a controlled-release dosage form. The HPMC is typically mixed with the active ingredient and other excipients to form a matrix that releases the drug at a controlled rate over an extended period of time. The matrix can be incorporated into tablets, capsules, or other dosage forms.

Here are some of the main advantages of using HPMC in pharmaceutical applications:

Safety:

HPMC is derived from natural cellulose and is considered safe for human consumption. It is widely used in pharmaceutical applications and has a long history of safe use.

Biodegradability:

HPMC is biodegradable and does not accumulate in the environment, making it an environmentally friendly option for the pharmaceutical industry.

Versatility:

HPMC can be used in a wide range of applications in the pharmaceutical industry, including as a binder, disintegrant, suspending agent, and film coating agent.

Controlled release:

HPMC can be used to create controlled-release formulations that release the drug at a controlled rate over an extended period of time. This can improve the efficacy of the drug and reduce the frequency of dosing.

Improved stability:

HPMC can improve the stability of drug formulations by preventing degradation and improving shelf life. It can also protect the drug from environmental factors, such as light and humidity.

Improved patient compliance:

HPMC can be used to improve the appearance, taste, and swallowability of drug products, which can improve patient compliance and adherence to treatment.


Advantages of Hpmc for Pharmaceutical

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Global News About Cellulose Ether
Global News About Cellulose Ether