Name: HPMC K100M
Brand: KIMA CHEMICAL CO.,LTD.
Availability: InStock
Rating: 4.8 (50 reviews)

Specification of HPMC K100M

HPMC K100M ( 9004 65 3 ) Hydroxypropyl Methyl Cellulose (HPMC)
Physical Analysis
Appearance	White to slightly off-white fibrous or granular powder.
Identification A to E	Conform
Solution appearance	Conform
Methoxy	19.0-24.0%
Hydroxypropoxy	4.0-12.0%
Loss on drying	5.0% Max
Residue on ignition	1.5% Max
pH	5.0-8.0
Apparent viscosity	80000.0-120000.0cps
Particle size	Min. 98% pass through 100 mesh
Heavy Metals
Heavy Metal	≤10ppm
Arsenic	≤3ppm
Lead	≤3ppm
Mercury	≤1ppm
Cadmium	≤1ppm
Micro bacteria
Total plate count	≤1000cfu/g
Yeast and Mould	≤100cfu/g
Coli form	Absent/g
Salmonella	Absent/g

Application of HPMC K100M

KimaCell^® HPMC K100M is used in Gel micelles prepared for drug delivery.

Micelles usually refer to amphiphilic block copolymers (one end is a hydrophilic polymer and the other end is a hydrophobic polymer) when a critical concentration is reached in a solution, which is formed by intermolecular hydrogen bonds, van der Waals forces, and hydrophobic interactions. A core-shell structure with spontaneously formed nanoscale hydrophilic outer shell and hydrophobic inner shell. This hollow structure can store drug molecules and can be used as a drug carrier. The co-solvent evaporation method (spray drying and rotary evaporation to dry the solvent) made the low-viscosity grade polymer HPMC into micelles for the efficient encapsulation of the low water-soluble drug simvastatin to improve the dissolution rate and bioavailability of the drug.

Documents of HPMC K100M

HPMC K100M Material Safety Data Sheet

HPMC K100M Technical Data Sheet

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